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KONDO Hidehiro
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Research Interests 【 display / non-display 】
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血球凝集
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血球凝集因子
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DNAワクチン
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Edwardsiella tarda
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Lactococcus garvieae
Research Areas 【 display / non-display 】
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Life Science / Aquatic life science
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Life Science / Aquatic bioproduction science
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Life Science / Aquatic life science
Papers 【 display / non-display 】
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Effects of anti-rainbow trout germ-cell monoclonal antibody on germ cells and gonadal tissues in rainbow trout (Oncorhynchus mykiss)
Kenji Takase, Akihiro Harakawa, Masaki Yokota, Lik-Ming Lau, Yuichi Amano, Kensuke Ichida, Keiichiro Koiwai, Ikuo Hirono, Hidehiro Kondo , 2025.01
Aquaculture
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Application of nervous necrosis virus capsid protein-based antigen-presenting particles for vaccine development.
Sajee Wayha, Keiichiro Koiwai, Motohiko Sano, Ikuo Hirono, Hidehiro Kondo , 2024.09
Fish & shellfish immunology
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Characterization of Photobacterium damselae subsp. damselae isolated from diseased Asian seabass (Lates calcarifer) and the preliminary development of a formalin-killed cell vaccine.
Warisara Weawsawang, Theeyathart Homsombat, Saransiri Nuanmanee, Nattakan Saleetid, Jumroensri Thawonsuwan, Ansaya Pumchan, Ikuo Hirono, Hidehiro Kondo, Sasimanas Unajak , 2024.07
Journal of fish diseases
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Systemic immune responses do not affect significant immune responses in the skin.
Soichiro Yoshizawa, Yuki Ishida, Chihiro Nakashima, Fuyuka Murotani, Tomouiki Hara, Keisuke Yoshii, Hidetoshi Yamada, Yutaka Fukuda, Reiko Nozaki, Keiichiro Koiwai, Ikuo Hirono, Hidehiro Kondo , 2024.07
Fish & shellfish immunology
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Investigating the impact of chlorine dioxide in shrimp-rearing water on the stomach microbiome, gill transcriptome, and infection-related mortality in shrimp.
Kentaro Imaizumi, Reiko Nozaki, Kayo Konishi, Hideaki Tagishi, Takanori Miura, Hidehiro Kondo, Ikuo Hirono , 2024.07
Journal of applied microbiology
Books 【 display / non-display 】
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水圏生化学の基礎
渡部終五編 , 2009.05
恒星社厚生閣 , 第9章3節 細胞の情報伝達 , 215-222
Grant-in-Aid for Scientific Research 【 display / non-display 】
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魚類における耐病性責任遺伝子を用いた宿主と病原体の史的攻防メカニズムの解明
Project Period (FY): 2024/04 - 2028/03 Investigator(s): 坂本 崇
Grant-in-Aid for Scientific Research(A) Co-Investigator 24H00521
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Project Period (FY): 2023/04 - 2028/03 Investigator(s): 佐野 元彦
Grant-in-Aid for Scientific Research(A) Co-Investigator 23H00343
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Project Period (FY): 2022/04 - 2026/03 Investigator(s): 廣野 育生
Grant-in-Aid for Scientific Research(A) Co-Investigator 22H00379
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Molecular characterization of virulence mechanisms of shrimp pathogenic virus WSSV
Project Period (FY): 2019/04 - 2023/03 Investigator(s): Hirono Ikuo
Grant-in-Aid for Scientific Research(A) Co-Investigator 19H00949
White spot syndrome virus (WSSV) and WSSV like fossilized virus genomes were amplified by the long PCR method to obtain a region covering the entire genome as seven DNA fragments. We attempted to introduce foreign DNA into the cells of the shrimp using various reagents and electroporation methods, but no expression of the introduced genes was observed. We also tried to introduce DNA into primary cultured cells of the shrimp, but were unable to do so. It is necessary to examine whether there is a problem in the expression of the introduced gene. Comparison of genomes of WSSV of different isolates showed differences in sequences where amino acid substitutions occur, suggesting that several genes are associated with virulence intensity. We obtained sequences transcribed from genes encoded in WSSV like fossilized virus genomes.
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Translated with www.DeepL.com/Translator (free version) -
Regulation of sexual maturation of fish by using gonad specific antibodies
Project Period (FY): 2018/06 - 2020/03 Investigator(s): Kondo Hidehiro
Grant-in-Aid for challenging Research (Exploratory) Principal Investigator 18K19227
The value and quality of aquaculture products are strongly affected by the gonadal development of fish. The control of gonadal development may allow us to produce the fish more efficiently. In this study, we attempted to develop a method to control the gonadal development of rainbow trout Oncorhynchus mykiss by administrating specific antibodies against the gonadotropin receptors. We developed the specific antiserum against the fish follicle stimulating hormone and luteinizing hormone by immunizing rabbits and purified the IgG as the specific antibodies. On 6 months after the first administration of the antibodies, the antibody injected fish were larger than the controls; however, the gonads in the fish were more developed.
Lesson Subject 【 display / non-display 】
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Lesson Subject(Undergraduate)
Genetic Engineering
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Lesson Subject(Graduate School)
Advanced Research in Applied Bio Engineering
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Special Seminar in Marine Bio Engineering
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Research in Marine Bio Engineering
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Genome Science of Fish and Shellfish